ABSTRACT
The occurrence of high intraocular pressure (IOP) after vitrectomy for diabetic retinopathy (DR) is related to many factors,including the type and stage of DR,macular detachment,surgical methods,and the type of ocular tamponade.Early high IOP occurred mainly due to laser photocoagulation,inflammatory response,improper ocular tamponade,residual viscoelastic agents and ciliary body dysfunction.In addition to the above reasons,early-middle stage high IOP is also related to tamponade gas expansion peak,encircling scleral buckle and hyphema.The major reason for middle-stage high IOP is hyphema and silicon oil in anterior chamber.The reasons for late-stage high IOP are glaucoma,silicone oil emulsification,long-term use of glucocorticoid,and iris incision closure.Most high IOP can be controlled by proper treatment such as stopping use of glucocorticoid,anti-glaucoma eye drops and surgeries.But there are still a small number of patients with unexplained refractory high IOP,the mechanism need to be further explored.
ABSTRACT
Objective To investigate the risk factors of the intraocular pressure (IOP) elevation after pars plana vitrectomy (PPV). Methods Eighty eight patients (88 eyes) of postoperative ocular hypertension in a series of 339 patients who had undergone PPV with normal ocular pressure before operation were retrospectively studied. The ocular pressures in both preoperative and postoperative periods were detected by NCT examination, and the ocular hypertension was decided on the level of ≥25 mm Hg. The relationships of occurence of the time of onset and duration of persistence of postoperative ocular hypertension with the different kinds of primary diseases, the techniques of operation, and the condition whether or not the affected eyes had formerly accepted surgical intervention, were analyzed. Results The IOP elevation occures mostly within 1 to 2 weeks postoperatively (77 eyes, 87.5%). In 65 cases (65 eyes) IOP returned to normal in 1 week, and in another 14 cases (14 eyes) in 1 month after treatments. Six patients' (6 eyes ) IOP was under 25 to 30 mm Hg with the medicine. With sustained elevation of IOP over 4 to 6 months, 3 cases (3 eyes ) lost or almost lost their vision finally. The probability of postoperative IOP elevation in the patients suffered from the retinal detachment with proliferative vitreoretinopathy (PVR) ≥grade C 2 was the highest in all the patients in our study (38.2%, P